Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271381 | 0.90 | SIRT6 (0.81) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL6151230 | 0.90 | SIRT6 (0.81) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL7048817 | 0.85 | MAPT (0.85) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL12952781 | 0.83 | SIRT6 (0.71) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL378458 | 0.82 | MAPT (0.96) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL1851861 | 0.82 | MAPT (0.89) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL13159166 | 0.81 | SIRT6 (0.69) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL20639764 | 0.81 | SIRT6 (0.69) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL12240580 | 0.81 | SIRT6 (0.74) | POLBSIRT6MAPTALDH1A1ADRB1 | |
| SCHEMBL447471 | 0.81 | SIRT6 (1.00) | POLBSIRT6MAPTALDH1A1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354901-A | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2023-06-30 | — | — | CN | claimed |
| CN-116354901-B | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116354901-A | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2023-06-30 | — | — | CN | disclosed |