Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 9/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 9/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 9/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 9/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 9/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280289 | 0.85 | GAA (0.41) | KMT2AGAAMAPTTHRBTDP1 | |
| SCHEMBL16102468 | 0.81 | KMT2A (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16094126 | 0.81 | KMT2A (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7305249 | 0.81 | ALDH1A1 (0.42) | BCHEACHE | |
| SCHEMBL16119912 | 0.81 | KMT2A (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20868275 | 0.77 | NR3C1 (0.33) | KMT2AMAPT | |
| SCHEMBL25207180 | 0.75 | ALDH1A1 (0.36) | ENPP3ENPP1ENPP2GAAMAPT | |
| SCHEMBL14779262 | 0.74 | GAA (0.46) | KMT2AGAA | |
| SCHEMBL27916949 | 0.74 | CYP1A2 (0.47) | KMT2AGAAMAPTBCHEACHE | |
| SCHEMBL9839980 | 0.73 | GAA (0.42) | KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212830-B | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-111212830-A | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2020-05-29 | — | — | CN | disclosed |