Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344307 | 0.85 | PDE10A (0.50) | ALDH1A1L3MBTL1LMNAPOLBTDP1 | |
| SCHEMBL6597210 | 0.84 | MAPT (0.60) | ALDH1A1L3MBTL1LMNANPC1MAPT | |
| SCHEMBL3381186 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBTDP1NPC1 | |
| SCHEMBL305884 | 0.82 | PDE10A (0.53) | ALDH1A1LMNAPOLBTDP1NPC1 | |
| SCHEMBL1231901 | 0.82 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBNPC1MAPT | |
| SCHEMBL1232905 | 0.81 | KDM4E (0.54) | ALDH1A1L3MBTL1LMNAPOLBTDP1 | |
| SCHEMBL5656450 | 0.80 | TDP1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBTDP1 | |
| SCHEMBL7049057 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBTDP1NPC1 | |
| SCHEMBL8565503 | 0.79 | PDE10A (0.50) | ALDH1A1LMNAPOLBTDP1NPC1 | |
| SCHEMBL28228342 | 0.79 | PDE10A (0.50) | ALDH1A1L3MBTL1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |