Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305884 | 0.85 | PDE10A (0.53) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL1232905 | 0.84 | KDM4E (0.54) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL3381186 | 0.82 | ALDH1A1 (0.51) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL8565503 | 0.82 | PDE10A (0.50) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL27344307 | 0.81 | PDE10A (0.50) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL7049057 | 0.79 | ALDH1A1 (0.49) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL29028896 | 0.79 | ALDH1A1 (0.60) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL6448689 | 0.79 | PDE10A (0.50) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL24377212 | 0.78 | CTSD (0.57) | PDE10APOLBALDH1A1NPC1MEN1 | |
| SCHEMBL11724759 | 0.78 | ALDH1A1 (0.48) | PDE10APOLBALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276382-A | Cell cycle protein dependent kinase inhibitor and its application | 南京圣和药业股份有限公司 | 2018-07-13 | — | — | CN | disclosed |