SCHEMBL29029147

SCHEMBL29029147

O=C(O)c1c(Cl)ccc(-c2ccccc2)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 1/20 0.53
DPP4 P27487 1/20 0.48
FABP3 P05413 1/20 0.45
FABP4 P15090 1/20 0.45
CYP2A6 P11509 1/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PRKAB2 O43741 2/20 0.41
PRKAG1 P54619 2/20 0.41
PRKAA2 P54646 2/20 0.41
PRKAA1 Q13131 2/20 0.41
PRKAG3 Q9UGI9 2/20 0.41
PRKAG2 Q9UGJ0 2/20 0.41
PRKAB1 Q9Y478 2/20 0.41
FOLH1 Q04609 1/20 0.40
PBRM1 Q86U86 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27703247 0.86 DPP4 (0.50) CLCN2DPP4FABP3FABP4CYP2A6
SCHEMBL7684364 0.85 CLCN2 (0.47) CLCN2CYP2A6ALDH1A1MEN1KMT2A
SCHEMBL5567625 0.85 DPP4 (0.50) CLCN2DPP4ALDH1A1KDM4EHSD17B10
SCHEMBL27592619 0.83 DPP4 (0.62) CLCN2DPP4FABP3FABP4CYP2A6
SCHEMBL28701648 0.83 CLCN2 (0.44) CLCN2FABP3FABP4CYP2A6ALDH1A1
SCHEMBL2370422 0.79 DPP4 (0.43) CLCN2DPP4FABP3FABP4CYP2A6
SCHEMBL31212990 0.78 CYP2A6 (0.56) DPP4FABP3FABP4CYP2A6ALDH1A1
SCHEMBL2136910 0.78 CYP2A6 (0.56) DPP4FABP3FABP4CYP2A6ALDH1A1
SCHEMBL27818395 0.78 NPSR1 (0.41) CLCN2ALDH1A1KDM4E
SCHEMBL28788982 0.78 FABP4 (0.46) CLCN2FABP3FABP4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396215-A Preparation method for hydrolyzing cyano compound into carboxyl compound 苏利(宁夏)新材料科技有限公司 2023-07-07 CN disclosed