SCHEMBL7684364

SCHEMBL7684364

O=C(c1ccccc1)c1c(Cl)ccc(-c2ccccc2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 1/20 0.47
ALDH1A1 P00352 3/20 0.46
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CNR2 P34972 1/20 0.42
SRD5A2 P31213 2/20 0.41
CYP2A6 P11509 1/20 0.41
VCAM1 P19320 1/20 0.41
GRM6 O15303 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
XBP1 P17861 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29029147 0.85 CLCN2 (0.53) CLCN2ALDH1A1CYP2A6MEN1KMT2A
SCHEMBL11210134 0.78 MEN1 (0.50) CLCN2ALDH1A1CNR2SRD5A2VCAM1
SCHEMBL6747845 0.76 ALDH1A1 (0.46) ALDH1A1CNR2SRD5A2VCAM1L3MBTL1
SCHEMBL8608656 0.76 ALDH1A1 (0.46) ALDH1A1CNR2SRD5A2VCAM1L3MBTL1
SCHEMBL30015375 0.76 ALDH1A1 (0.46) ALDH1A1CNR2SRD5A2VCAM1L3MBTL1
SCHEMBL7581152 0.76 ALDH1A1 (0.46) CLCN2ALDH1A1SRD5A2VCAM1L3MBTL1
SCHEMBL27703247 0.76 DPP4 (0.50) CLCN2ALDH1A1CYP2A6MEN1KMT2A
SCHEMBL1042856 0.74 ALDH1A1 (0.59) ALDH1A1SRD5A2L3MBTL1MEN1LMNA
SCHEMBL1666435 0.74 ALDH1A1 (0.58) ALDH1A1L3MBTL1MEN1LMNAXBP1
SCHEMBL16316326 0.74 CLCN2 (0.48) CLCN2ALDH1A1VCAM1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476055-B1 5,5-disubstituted thiazolidine derivative pesticides NIPPON SODA CO. LTD. (JP) 2002-11-05 US disclosed