Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730506 | 0.93 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6869447 | 0.93 | LMNA (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL23899079 | 0.90 | NAMPT (0.65) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8191789 | 0.90 | RXFP1 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL3460916 | 0.90 | KMT2A (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL23119695 | 0.90 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20057652 | 0.90 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL526864 | 0.90 | SYK (0.60) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8966117 | 0.90 | HSD17B10 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29991501 | 0.90 | HSD17B10 (0.59) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661387-B | Composition for treating pulmonary fibrosis | 维克图斯生物系统有限公司 | 2023-05-30 | — | — | CN | disclosed |