SCHEMBL29029474

SCHEMBL29029474

CC[C@H](C(=O)O)S(C)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 1/20 0.35
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 1/20 0.34
MAPK1 P28482 1/20 0.34
GCLC P48506 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
MMP2 P08253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5761 1.00 PMP22 (0.35) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL16782030 0.80 PMP22 (0.42) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL28224631 0.80 HDAC1 (0.48) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL890709 0.79 CHRM1 (0.40) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL7241006 0.79 CHRM1 (0.35) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL16588883 0.78 PMP22 (0.37) PMP22GCLCSLC1A3SLC1A2SLC1A1
SCHEMBL5022363 0.77 CHRM1 (0.39) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL5014288 0.77 CHRM1 (0.39) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL5013300 0.77 CHRM1 (0.39) PMP22CHRM1AKR1A1CHRM3HTR2A
SCHEMBL1634572 0.77 MMP2 (0.35) PMP22CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217426-A Method for synthesizing S-fluorobutyramide from (R) -2-sulfonyl butyrate alkyl ester 山东省农药科学研究院 2023-06-06 CN disclosed