Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542043 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL4951809 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL10636579 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL18434657 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL16375430 | 0.87 | KMT2A (0.77) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL12489991 | 0.87 | PKM (0.77) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL3145157 | 0.87 | KMT2A (0.77) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL26355639 | 0.86 | KMT2A (0.75) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL9135711 | 0.85 | KMT2A (0.74) | KMT2APKMHGFACALDH1A1MAPT | |
| SCHEMBL9786893 | 0.85 | KMT2A (0.74) | KMT2APKMHGFACALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4563573-A1 | COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PREPARATION OF SEH INHIBITOR AND PPARS AGONIST | Shenyang Pharmaceutical University (CN) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024193129-A1 | COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PREPARATION OF SEH INHIBITOR AND PPARS AGONIST | 沈阳药科大学 | 2024-09-26 | — | — | WO | disclosed |
| CN-118206542-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118206473-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118184545-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-116217511-B | Double-target compound, preparation method thereof and application thereof in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-116217511-A | Double-target compound, preparation method thereof and application thereof in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2023-06-06 | — | — | CN | disclosed |