Sugi Predict

Sugi Predict / Compounds / SCHEMBL4951809

SCHEMBL4951809

SCHEMBL4951809

O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccc(C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.84
▸ PKM P14618 1/20 0.84
▸ HGFAC Q04756 1/20 0.72
▸ MAPT P10636 4/20 0.65
▸ ALDH1A1 P00352 3/20 0.65
▸ NR1H4 Q96RI1 1/20 0.62
▸ GAA P10253 2/20 0.61
▸ HPGD P15428 1/20 0.61
▸ ALOX5 P09917 1/20 0.60
▸ CES1 P23141 1/20 0.59
▸ CA1 P00915 2/20 0.57
▸ CA2 P00918 2/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ HTT P42858 1/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ BCL9 O00512 1/20 0.56
▸ CTNNB1 P35222 1/20 0.56
▸ SRD5A2 P31213 1/20 0.56
▸ XDH P47989 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542043 1.00 KMT2A (0.84) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL18434657 1.00 KMT2A (0.84) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL10636579 1.00 KMT2A (0.84) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL3145157 0.95 KMT2A (0.77) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL16375430 0.95 KMT2A (0.77) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL12489991 0.95 PKM (0.77) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL9786893 0.93 KMT2A (0.74) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL9135711 0.93 KMT2A (0.74) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL8202880 0.93 KMT2A (0.74) KMT2APKMHGFACMAPTALDH1A1
SCHEMBL11613038 0.93 KMT2A (0.74) KMT2APKMHGFACMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140147687-A1 BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-05-29 — — US disclosed
US-20140147686-A1 BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-05-29 — — US disclosed
US-20080146768-A1 PROCESSES FOR PREPARING POLYMERS USING ALPHA,OMEGA-DIFUNCTIONAL ALDARAMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-19 — — US disclosed
EP-1858955-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-11-28 — — EP disclosed
US-20060264672-A1 Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers E. I. DU PONT DE NEMOURS AND COMPANY 2006-11-23 — — US disclosed
WO-2006091901-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-08-31 — — WO disclosed
US-20050208091-A1 Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-09-22 — — US disclosed
US-4085164-A MOLDING MATERIALS, ADHESIVES, LAMINATES, COATINGS RHONE-POULENC INDUSTRIES (FR) 1978-04-18 — — US disclosed
US-4064193-A Heat-resistant polymers based on polyamines and oligomers possessing imide groups with unsaturated polyester RHONE-POULENC S.A. (FR) 1977-12-20 — — US disclosed
US-4064192-A Heat-stable polyimide resins RHONE-POULENC S.A. (FR) 1977-12-20 — — US disclosed
US-4039628-A Heat-stable polyimide resins RHONE-POULENC S.A. (FR) 1977-08-02 — — US disclosed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 — — US disclosed
US-4012361-A Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine RHONE-POULENC S.A. (FR) 1977-03-15 — — US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 — — US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 — — US disclosed
US-4004959-A Unsaturated polyester with polyimide-ammonia prepolymers as thermosetting laminate RHONE-POULENC INDUSTRIES (FR) 1977-01-25 — — US disclosed
US-3998787-A Heat-stable polyimide resins from bis-imide and aldehyde-azine BARGAIN MICHEL 1976-12-21 — — US disclosed
US-3972960-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-08-03 — — US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264672-A1 Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers ALOX5, GSTO1, FASN KMT2A 3311/4885PKM 2671/4885HGFAC 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.