Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029516 | 1.00 | GSK3B (0.57) | GSK3BCLK1DYRK1AHPGDLMNA | |
| SCHEMBL29029500 | 0.80 | HPGD (0.78) | HPGDRAB9A | |
| SCHEMBL29029499 | 0.80 | HPGD (0.78) | HPGDRAB9A | |
| SCHEMBL12821680 | 0.75 | GSK3B (0.81) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL12821679 | 0.75 | GSK3B (0.81) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL209319 | 0.75 | HRH1 (0.59) | HPGDHRH1PTPN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23086789 | 0.73 | HRH1 (0.58) | HPGDHRH1PTPN1ALDH1A1 | |
| SCHEMBL1247645 | 0.73 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL1247647 | 0.73 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT | |
| SCHEMBL15421958 | 0.73 | GSK3B (1.00) | GSK3BCLK1DYRK1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206473-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118206542-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118184545-A | Compound, preparation method thereof and application of compound in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-116217511-B | Double-target compound, preparation method thereof and application thereof in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-116217511-A | Double-target compound, preparation method thereof and application thereof in preparation of sEH inhibitor and PPARs agonist | 沈阳药科大学 | 2023-06-06 | — | — | CN | disclosed |