Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 1.00 |
| ▸ | CLK1 | P49759 | 2/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 1.00 |
| ▸ | METAP1 | P53582 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.59 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15421958 | 1.00 | GSK3B (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL1247647 | 1.00 | GSK3B (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL12821679 | 0.85 | GSK3B (0.81) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL12821680 | 0.85 | GSK3B (0.81) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL2894955 | 0.84 | METAP1 (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL15421319 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL15421317 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL15421318 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL11353972 | 0.83 | GSK3B (0.71) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL4469105 | 0.82 | GSK3B (0.69) | GSK3BCLK1DYRK1AMETAP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | claimed |
| JP-5345713-A | — | — | None | — | — | JP | disclosed |
| US-9896421-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2018-02-20 | — | — | US | disclosed |
| EP-2832727-B1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMA (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9422246-B2 | Benzylidene azolidine derivative or salt thereof | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2016-08-23 | — | — | US | disclosed |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | disclosed |
| US-9216148-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-12-22 | — | — | US | disclosed |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2832727-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | Rohto Pharmaceutical Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |
| US-20140023603-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2014-01-23 | — | — | US | disclosed |
| WO-2004080481-A1 | NOVEL NPH INSULIN PREPARATIONS | NOVO NORDISK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004080480-A1 | PHARMACEUTICAL PREPARATIONS COMPRISING ACID-STABILISED INSULIN | NOVO NORDISK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004056347-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
| EP-1429763-A2 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-20030229120-A1 | Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer | NOVO NORDISK A/S (DK) | 2003-12-11 | — | — | US | disclosed |
| WO-2003027081-A2 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2003-04-03 | — | — | WO | disclosed |
| JP-H05345713-A | EXTERNAL PREPARATION FOR SKIN | KAO CORP | 1993-12-27 | — | — | JP | disclosed |
| EP-0156582-B1 | PROCESS FOR THE PREPARATION OF DL-BETA-ARYL AMINO ACIDS | ALKALOIDA VEGYESZETI GYAR (HU) | 1988-09-14 | — | — | EP | disclosed |
| US-4672127-A | Process for production of hydantoin derivatives | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1987-06-09 | — | — | US | disclosed |
| US-4647694-A | Process for the preparation of D1-β-aryl amino acids | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140023603-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | PPARG, PPARA, PPARD | GSK3B 2733/4885CLK1 4209/4885DYRK1A 3884/4885 |
| US-20030229120-A1 | Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer | IAPP, IRS1, GPR119 | GSK3B 4545/4885CLK1 3972/4885DYRK1A 4301/4885 |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | GSK3B 3223/4885CLK1 3520/4885DYRK1A 3727/4885 |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | IL4I1, SLC6A19, SLC9B2 | GSK3B 4546/4885CLK1 4412/4885DYRK1A 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.