Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 1.00 |
| ▸ | CLK1 | P49759 | 2/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 1.00 |
| ▸ | METAP1 | P53582 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.59 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247645 | 1.00 | GSK3B (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL15421958 | 1.00 | GSK3B (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL12821679 | 0.85 | GSK3B (0.81) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL12821680 | 0.85 | GSK3B (0.81) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL2894955 | 0.84 | METAP1 (1.00) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL15421319 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL15421317 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL15421318 | 0.83 | CLK1 (0.71) | GSK3BCLK1DYRK1AMETAP1RAB9A | |
| SCHEMBL11353972 | 0.83 | GSK3B (0.71) | GSK3BCLK1DYRK1AMETAP1POLB | |
| SCHEMBL4469105 | 0.82 | GSK3B (0.69) | GSK3BCLK1DYRK1AMETAP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | claimed |
| JP-5345713-A | — | — | None | — | — | JP | disclosed |
| US-9896421-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2018-02-20 | — | — | US | disclosed |
| EP-2832727-B1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMA (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9422246-B2 | Benzylidene azolidine derivative or salt thereof | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2016-08-23 | — | — | US | disclosed |
| CN-104203923-B | New benzylidene pyrrolidin derivatives or its salt | 乐敦制药株式会社 | 2016-08-10 | — | — | CN | disclosed |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | disclosed |
| US-9216148-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-12-22 | — | — | US | disclosed |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2832727-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | Rohto Pharmaceutical Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |
| US-4647694-A | Process for the preparation of D1-β-aryl amino acids | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-03-03 | — | — | US | disclosed |
| EP-0037480-B1 | PROCESS FOR THE PREPARATION OF 5-ARYLIDENEHYDANTOINS | Degussa Aktiengesellschaft (DE) | 1983-09-28 | — | — | EP | disclosed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0037479-A1 | Process for the preparation of 5-arylidenehydantoins | Degussa Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0037480-A1 | Process for the preparation of 5-arylidenehydantoins | Degussa Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4264617-A | VIRICIDES, VETERNARY MEDICINE | CANADA PACKERS, LIMITED (CA) | 1981-04-28 | — | — | US | disclosed |
| US-4111923-A | LUTEINIZING HORMONE RELEASING FACTOR ANTAGONISTS | PARKE, DAVIS & COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4065571-A | Antiviral 5-(substituted benzal) hydantoins | CANADA PACKERS LIMITED (CA) | 1977-12-27 | — | — | US | disclosed |
| US-4065570-A | Antiviral 5-(substituted benzal) hydantoins | CANADA PACKERS LIMITED (CA) | 1977-12-27 | — | — | US | disclosed |
| US-4013770-A | PICORNA VIRUSES | CANADA PACKERS LIMITED (CA) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | GSK3B 3223/4885CLK1 3520/4885DYRK1A 3727/4885 |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | IL4I1, SLC6A19, SLC9B2 | GSK3B 4546/4885CLK1 4412/4885DYRK1A 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.