SCHEMBL29029660

SCHEMBL29029660

NC(=O)CCC(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.53
L3MBTL1 Q9Y468 4/20 0.45
TDP1 Q9NUW8 4/20 0.45
MAPT P10636 4/20 0.45
BLM P54132 2/20 0.45
PMP22 Q01453 2/20 0.45
CYP2C19 P33261 2/20 0.45
CYP3A4 P08684 2/20 0.45
POLB P06746 1/20 0.45
PARP1 P09874 1/20 0.45
TSHR P16473 1/20 0.45
RECQL P46063 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CTNNB1 P35222 1/20 0.44
LMNA P02545 3/20 0.42
CES1 P23141 2/20 0.42
CES2 O00748 1/20 0.42
MAPK1 P28482 2/20 0.42
NPC1 O15118 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017982 0.94 MDM2 (0.52) MDM2L3MBTL1TDP1MAPTBLM
SCHEMBL29029682 0.84 MDM2 (0.57) MDM2L3MBTL1TDP1MAPTCYP2C19
SCHEMBL29634956 0.83 BLM (0.53) MDM2L3MBTL1TDP1MAPTBLM
SCHEMBL10792592 0.78 MAPT (0.41) MDM2L3MBTL1TDP1MAPTBLM
SCHEMBL1970885 0.78 BLM (0.47) MDM2L3MBTL1TDP1MAPTBLM
SCHEMBL434807 0.76 MDM2 (0.57) MDM2L3MBTL1TDP1MAPTPOLB
SCHEMBL7929013 0.76 MDM2 (0.52) MDM2L3MBTL1TDP1MAPTCYP3A4
SCHEMBL10606306 0.74 MDM2 (0.50) MDM2L3MBTL1TDP1MAPTBLM
SCHEMBL29029678 0.74 MDM2 (0.50) MDM2L3MBTL1TDP1MAPTCYP2C19
SCHEMBL29029672 0.74 SMN1; SMN2 (0.48) MDM2L3MBTL1TDP1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN disclosed