SCHEMBL290301

SCHEMBL290301

C[C@H]1OC(=O)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
GBA1 P04062 1/20 0.50
HIF1A Q16665 2/20 0.41
DNMT1 P26358 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MANBA O00462 1/20 0.41
IDUA P35475 1/20 0.41
THRB P10828 1/20 0.41
GUSB P08236 1/20 0.41
CYP2C19 P33261 1/20 0.36
PPARG P37231 4/20 0.33
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
PMP22 Q01453 1/20 0.31
HBB P68871 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151964 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL17956707 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL977551 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL15947392 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL879339 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL12189851 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL15945043 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL12762744 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL9143456 0.92
SCHEMBL22106635 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210089-A Alpha and beta-mannosidase inhibitors MONSANTO COMPANY (US) 1993-05-11 US claimed
US-11286466-B2 Ketoreductases C-LECTA GMBH (DE) 2022-03-29 US disclosed
US-20200216821-A1 KETOREDUCTASES C-LECTA GMBH (DE) 2020-07-09 US disclosed
EP-3652328-A1 KETOREDUCTASES c-LEcta GmbH (DE) 2020-05-20 EP disclosed
WO-2019012095-A1 KETOREDUCTASES C-LECTA GMBH (DE) 2019-01-17 WO disclosed
US-9359581-B2 Biotransformation using genetically modified Candida SYNTHEZYME LLC (US) 2016-06-07 US disclosed
US-20150218486-A1 OXIDATION OF COMPOUNDS USING GENETICALLY MODIFIED CANDIDA SYNTHEZYME LLC (US) 2015-08-06 US disclosed
US-20150094483-A1 BIOTRANSFORMATION USING GENETICALLY MODIFIED CANDIDA INC., DNA TWOPOINTO, INC. 2015-04-02 US disclosed
US-8597923-B2 Oxidation of compounds using genetically modified Candida SyntheZyme, LLC (US) 2013-12-03 US disclosed
EP-2427559-A2 BIOTRANSFORMATION USING GENETICALLY MODIFIED CANDIDA DNA TWOPOINTO INC. (US) 2012-03-14 EP disclosed
WO-2011008231-A2 BIOTRANSFORMATION USING GENETICALLY MODIFIED CANDIDA DNA 2.0 INC. (US) 2011-01-20 WO disclosed
US-20100291653-A1 BIOTRANSFORMATION USING GENETICALLY MODIFIED CANDIDA INC., DNA TWOPOINTO, INC. 2010-11-18 US disclosed
US-5210089-A Alpha and beta-mannosidase inhibitors MONSANTO COMPANY (US) 1993-05-11 US disclosed
US-5210089-A Alpha and beta-mannosidase inhibitors MONSANTO COMPANY (US) 1993-05-11 US disclosed
US-5210089-A Alpha and beta-mannosidase inhibitors MONSANTO COMPANY (US) 1993-05-11 US disclosed