SCHEMBL977551

SCHEMBL977551

C[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
GBA1 P04062 1/20 0.50
HIF1A Q16665 2/20 0.41
DNMT1 P26358 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MANBA O00462 1/20 0.41
IDUA P35475 1/20 0.41
THRB P10828 1/20 0.41
GUSB P08236 1/20 0.41
CYP2C19 P33261 1/20 0.36
PPARG P37231 4/20 0.33
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
PMP22 Q01453 1/20 0.31
HBB P68871 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151964 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL290301 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL17956707 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL15947392 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL879339 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL12189851 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL15945043 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL12762744 1.00 LMNA (0.50) LMNAGBA1HIF1ADNMT1CTDSP1
SCHEMBL9143456 0.92
SCHEMBL22106635 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
US-4064277-A SOYBEAN MILK, BETA-GLYCOSIDASE KIKKOMAN SHOYU CO., LTD. (JA) 1977-12-20 US claimed
US-11433025-B2 Oil foamable carriers and formulations VYNE THERAPEUTICS INC. (US) 2022-09-06 US disclosed
US-20170181970-A1 Oil foamable carriers and formulations FOAMIX LTD. (IL) 2017-06-29 US disclosed
US-9636405-B2 Foamable vehicle and pharmaceutical compositions thereof FOAMIX PHARMACEUTICALS LTD. (IL) 2017-05-02 US disclosed
US-9549898-B2 Oil and liquid silicone foamable carriers and formulations FOAMIX PHARMACEUTICALS LTD. (IL) 2017-01-24 US disclosed
US-20150118164-A1 Oil and Liquid Silicone Foamable Carriers and Formulations SWK FUNDING LLC 2015-04-30 US disclosed
US-8900553-B2 Oil and liquid silicone foamable carriers and formulations FOAMIX PHARMACEUTICALS LTD. (IL) 2014-12-02 US disclosed
US-8795693-B2 Compositions with modulating agents FOAMIX LTD. (IL) 2014-08-05 US disclosed
US-20110212033-A1 OIL AND LIQUID SILICONE FOAMABLE CARRIERS AND FORMULATIONS FOAMIX LTD. (IL) 2011-09-01 US disclosed
EP-0403238-A2 Cosmetic composition UNILEVER PLC (GB) 1990-12-19 EP disclosed
US-4975441-A ENZYME INHIBITOR OF GLYCOSIDASE TO INCREASE HAIR GROWTH; TOPICAL UNILEVER PATENT HOLDINGS B.V. (NL) 1990-12-04 US disclosed
EP-0375388-A2 Cosmetic composition UNILEVER PLC (GB) 1990-06-27 EP disclosed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP disclosed
EP-0335554-A2 Cosmetic composition UNILEVER PLC (GB) 1989-10-04 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
US-4064277-A SOYBEAN MILK, BETA-GLYCOSIDASE KIKKOMAN SHOYU CO., LTD. (JA) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11433025-B2 Oil foamable carriers and formulations LIPA, PTGER1, TTPA LMNA 500/4885GBA1 148/4885HIF1A 2320/4885
US-20150118164-A1 Oil and Liquid Silicone Foamable Carriers and Formulations LIPA, LPXN, PTGER1 LMNA 281/4885GBA1 351/4885HIF1A 2646/4885
US-20110212033-A1 OIL AND LIQUID SILICONE FOAMABLE CARRIERS AND FORMULATIONS LIPA, LPXN, PTGER1 LMNA 281/4885GBA1 351/4885HIF1A 2646/4885
US-20170181970-A1 Oil foamable carriers and formulations LIPA, PTGER1, TTPA LMNA 500/4885GBA1 148/4885HIF1A 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.