Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030413 | 0.90 | TDP1 (0.53) | TDP1LMNAHDAC1PPARAESR1 | |
| SCHEMBL9815319 | 0.87 | TDP1 (0.53) | TDP1LMNAESR1SNCANPC1 | |
| SCHEMBL344616 | 0.85 | TDP1 (0.81) | TDP1LMNAESR1ESR2NPC1 | |
| SCHEMBL29030371 | 0.84 | LMNA (0.47) | TDP1LMNAESR1SNCANPC1 | |
| SCHEMBL29030437 | 0.83 | HDAC1 (0.53) | TDP1LMNAHDAC1PPARAPPARG | |
| SCHEMBL10660561 | 0.83 | SNCA (0.51) | TDP1LMNAESR1ESR2SNCA | |
| SCHEMBL25196319 | 0.83 | BCHE (0.55) | TDP1LMNAALDH1A1CYP3A4 | |
| SCHEMBL726435 | 0.83 | TDP1 (0.63) | TDP1LMNAESR1NPC1RAB9A | |
| SCHEMBL27517367 | 0.82 | TDP1 (0.56) | TDP1LMNAHDAC1NPC1RAB9A | |
| SCHEMBL13291875 | 0.82 | TDP1 (0.65) | TDP1LMNAESR1ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410365-A | Polypropylene catalyst and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116410367-A | Catalyst system for ethylene polymerization and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | disclosed |