Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 5/20 | 0.36 |
| ▸ | PRKACA | P17612 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 8/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661056 | 0.91 | PKM (0.39) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL21118338 | 0.91 | PTGS1 (0.37) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL29030690 | 0.88 | IDO1 (0.42) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL16706551 | 0.86 | IDO1 (0.42) | RPS6KB1ROCK1GSK3BPRKACAIDO1 | |
| SCHEMBL30449198 | 0.85 | IDO1 (0.42) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL122395 | 0.85 | IDO1 (0.42) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL19654570 | 0.85 | RPS6KB1 (0.35) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL21118140 | 0.85 | NOTUM (0.41) | RPS6KB1ROCK1GSK3BPRKACAIDO1 | |
| SCHEMBL17595464 | 0.85 | MAPT (0.35) | RPS6KB1ROCK1MEN1KMT2AGSK3B | |
| SCHEMBL16709409 | 0.84 | IDO1 (0.42) | RPS6KB1ROCK1GSK3BPRKACAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110343098-B | Oxadiazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-05-26 | — | — | CN | disclosed |