Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030690 | 0.87 | IDO1 (0.42) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL123581 | 0.87 | IDO1 (0.54) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL29376679 | 0.87 | IDO1 (0.54) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL29030673 | 0.86 | RPS6KB1 (0.43) | IDO1RPS6KB1L3MBTL1ROCK1GSK3B | |
| SCHEMBL19661056 | 0.85 | PKM (0.39) | IDO1RPS6KB1L3MBTL1ROCK1GSK3B | |
| SCHEMBL29030697 | 0.84 | RPS6KB1 (0.38) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL16706551 | 0.83 | IDO1 (0.42) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL21326485 | 0.82 | IDO1 (0.44) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL22001225 | 0.82 | IDO1 (0.38) | IDO1RPS6KB1ROCK1GSK3BPRKACA | |
| SCHEMBL21118338 | 0.80 | PTGS1 (0.37) | IDO1RPS6KB1ROCK1GSK3BPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110343098-B | Oxadiazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-05-26 | — | — | CN | disclosed |
| WO-2015070007-A1 | PROCESS FOR THE SYNTHESIS OF AN INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR | INCYTE CORPORATION (US) | 2015-05-14 | — | — | WO | disclosed |