Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639192 | 0.82 | SERPINE1 (0.56) | SERPINE1TNKS2PARP2TUBB4ATUBB | |
| SCHEMBL31014303 | 0.81 | ESR1 (0.50) | PDE3BPDE3ANPC1RAB9ASERPINE1 | |
| SCHEMBL5599610 | 0.78 | WHR1 (0.50) | PDE3BPDE3ANPC1MEN1RAB9A | |
| SCHEMBL16312435 | 0.78 | MAPT (0.51) | PDE3BPDE3AGUSBNPC1MEN1 | |
| SCHEMBL29639258 | 0.77 | PTGS2 (0.54) | NPC1MEN1RAB9AKMT2ASERPINE1 | |
| SCHEMBL29031845 | 0.77 | PTGS2 (0.54) | NPC1MEN1RAB9AKMT2ASERPINE1 | |
| SCHEMBL29639198 | 0.77 | PTGS2 (0.54) | NPC1MEN1RAB9AKMT2ASERPINE1 | |
| SCHEMBL29639174 | 0.77 | SERPINE1 (0.67) | MEN1KMT2AATMSERPINE1ESR1 | |
| SCHEMBL29031883 | 0.77 | SERPINE1 (0.67) | MEN1KMT2AATMSERPINE1ESR1 | |
| SCHEMBL30472324 | 0.76 | ESR1 (0.49) | SERPINE1ESR1ESR2TNKS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396206-A | Isoindolinone compound and preparation method and application thereof | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |