Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639174 | 1.00 | SERPINE1 (0.67) | SERPINE1ESR1ESR2KDM4EMAPT | |
| SCHEMBL16578789 | 0.90 | SERPINE1 (0.56) | SERPINE1ESR1ESR2KDM4EMAPT | |
| SCHEMBL29031885 | 0.90 | SERPINE1 (0.56) | SERPINE1ESR1ESR2KDM4EMAPT | |
| SCHEMBL30472330 | 0.90 | SERPINE1 (0.56) | SERPINE1ESR1ESR2KDM4EMAPT | |
| SCHEMBL29639169 | 0.85 | PTGS2 (0.56) | SERPINE1ESR1ESR2PTGS2HPGD | |
| SCHEMBL29031838 | 0.85 | PTGS2 (0.55) | SERPINE1ESR1ESR2KDM4EPTGS2 | |
| SCHEMBL29031884 | 0.85 | SERPINE1 (0.71) | SERPINE1ESR1ESR2PTGS2PARP1 | |
| SCHEMBL31014307 | 0.85 | SERPINE1 (0.71) | SERPINE1ESR1ESR2KDM4EPTGS2 | |
| SCHEMBL29031852 | 0.85 | PTGS2 (0.56) | SERPINE1ESR1ESR2PTGS2HPGD | |
| SCHEMBL30472337 | 0.85 | PTGS2 (0.55) | SERPINE1ESR1ESR2KDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396206-A | Isoindolinone compound and preparation method and application thereof | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |