Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032224 | 0.83 | MTNR1A (0.64) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7022938 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL29032165 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL29032151 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL29032155 | 0.78 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL30448741 | 0.78 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL4043404 | 0.76 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL30449793 | 0.76 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL31543672 | 0.76 | CYP1A2 (0.57) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL8609306 | 0.74 | MTNR1A (0.72) | MTNR1AMTNR1BKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249691-B | Bicyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-116249691-A | Bicyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-09 | — | — | CN | disclosed |