Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384221 | 0.99 | HPGD (0.51) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL28887694 | 0.96 | HPGD (0.50) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20598310 | 0.84 | CSF1R (0.55) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20598344 | 0.84 | CSF1R (0.55) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20598458 | 0.83 | IRAK4 (0.50) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL20598851 | 0.83 | CSF1R (0.54) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL28379236 | 0.82 | IRAK4 (0.69) | SMN1; SMN2KDM4EIRAK4ALDH1A1TSHR | |
| SCHEMBL29033319 | 0.82 | HPGD (0.42) | HPGDGAASMN1; SMN2KDM4ELMNA | |
| SCHEMBL28383182 | 0.81 | IRAK4 (0.68) | SMN1; SMN2KDM4EIRAK4ALDH1A1TSHR | |
| SCHEMBL20598446 | 0.81 | SRPK1 (0.52) | HPGDGAASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |