Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283252 | 0.79 | MEN1 (0.47) | ESR1ESR2MEN1KMT2ARECQL | |
| SCHEMBL14671273 | 0.75 | MEN1 (0.48) | ESR1ESR2MAOAMAOBTYR | |
| SCHEMBL4565328 | 0.75 | ESR1 (0.55) | ESR1ESR2MAOAMAOBKDM4E | |
| SCHEMBL17797155 | 0.75 | ALDH1A1 (0.47) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL13928848 | 0.74 | ALDH1A1 (0.46) | MAOBMEN1KMT2AKDM4ESTK17B | |
| SCHEMBL16120884 | 0.74 | ESR1 (0.54) | ESR1ESR2MAOAMAOBRECQL | |
| SCHEMBL1500283 | 0.72 | MAOA (0.51) | ESR1ESR2MAOAMAOBKDM4E | |
| SCHEMBL14671252 | 0.72 | ESR2 (0.46) | ESR1ESR2MAOAMAOBTYR | |
| SCHEMBL19387339 | 0.72 | ESR2 (0.46) | ESR1ESR2MAOAMAOBTYR | |
| SCHEMBL14701871 | 0.72 | ESR2 (0.46) | ESR1ESR2MAOAMAOBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444472-A | Effective synthesis method of 7-hydroxy 3-methyl ketocoumarin | 承德医学院 | 2023-07-18 | — | — | CN | claimed |
| CN-116444472-A | Effective synthesis method of 7-hydroxy 3-methyl ketocoumarin | 承德医学院 | 2023-07-18 | — | — | CN | disclosed |
| CN-116444472-A | Effective synthesis method of 7-hydroxy 3-methyl ketocoumarin | 承德医学院 | 2023-07-18 | — | — | CN | disclosed |
| CN-116444472-A | Effective synthesis method of 7-hydroxy 3-methyl ketocoumarin | 承德医学院 | 2023-07-18 | — | — | CN | disclosed |