SCHEMBL29033707

SCHEMBL29033707

CC(C)P(Cc1ccccc1)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.42
SIGMAR1 Q99720 4/20 0.42
SLC18A2 Q05940 1/20 0.42
TRPA1 O75762 2/20 0.41
SLC6A2 P23975 3/20 0.40
MAOA P21397 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP2A6 P11509 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP2D6 P10635 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.37
RIPK1 Q13546 1/20 0.35
CALM1 P0DP23 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236089 0.75 TAAR1 (0.44) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL9453231 0.75 TAAR1 (0.44) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL17529701 0.75 TAAR1 (0.44) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL706086 0.75 TAAR1 (0.44) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL15285895 0.71 TAAR1 (0.41) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
Bromide SCHEMBL6698343 0.71 TAAR1 (0.41) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL10308668 0.71 TAAR1 (0.46) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL15285550 0.71 TAAR1 (0.41) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
SCHEMBL15656642 0.70 TAAR1 (0.44) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2
Bromide SCHEMBL6698393 0.70 TAAR1 (0.40) TAAR1SIGMAR1SLC18A2TRPA1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444563-A Novel method for synthesizing triphosphine ligand 广东欧凯新材料有限公司 2023-07-18 CN disclosed