Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706086 | 0.76 | TAAR1 (0.44) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL11236089 | 0.76 | TAAR1 (0.44) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL16687835 | 0.73 | LOXL2 (0.43) | TAAR1SLC6A2CYP2D6LOXL2TP53 | |
| SCHEMBL15285550 | 0.73 | TAAR1 (0.41) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL25533379 | 0.72 | LOXL2 (0.48) | TAAR1SLC6A2CYP3A4LOXL2TP53 | |
| Bromide SCHEMBL6698777 | 0.71 | TAAR1 (0.40) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL29033707 | 0.71 | TAAR1 (0.42) | TAAR1SLC6A2CYP2D6LMNATP53 | |
| Bromide SCHEMBL6698393 | 0.71 | TAAR1 (0.40) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL9883765 | 0.71 | TAAR1 (0.40) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28077821 | 0.70 | LOXL2 (0.46) | TAAR1CYP3A4LOXL2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178714-A1 | Phosphorus-containing Compounds & Uses Thereof | ARIAD PHARMACEUTICALS, INC. (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178714-A1 | Phosphorus-containing Compounds & Uses Thereof | ALPP, ALPI, PHOSPHO1 | TAAR1 4398/4885SLC6A2 1228/4885CYP2D6 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.