Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470968 | 0.87 | ESR1 (0.33) | SLC6A2 | |
| SCHEMBL3683269 | 0.87 | TAAR1 (0.45) | TAAR1LMNATSHRALDH1A1IDO1 | |
| SCHEMBL1465904 | 0.83 | BCHE (0.37) | TAAR1SLC6A2CYP2D6LMNACYP1A2 | |
| SCHEMBL6055441 | 0.81 | RIPK1 (0.46) | TAAR1SLC6A2TP53CYP2D6LMNA | |
| SCHEMBL11236089 | 0.80 | TAAR1 (0.44) | TAAR1SLC6A2TP53CYP2D6LMNA | |
| SCHEMBL3678654 | 0.79 | ESR1 (0.42) | TAAR1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL4449614 | 0.78 | RIPK1 (0.34) | TAAR1SLC6A2CYP2D6LMNAALDH1A1 | |
| SCHEMBL3689005 | 0.78 | IDO1 (0.42) | TAAR1TP53CYP1A2TSHRIDO1 | |
| SCHEMBL1466062 | 0.78 | BCHE (0.34) | TAAR1SLC6A2 | |
| SCHEMBL28400003 | 0.78 | ESR1 (0.44) | TAAR1SLC6A2SLC18A2SIGMAR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650894-B | Amphoteric calixarene derivative, composite catalyst containing amphoteric calixarene derivative and application of amphoteric calixarene derivative | 北京旭阳科技有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-115304441-B | Preparation method of amide synthesized by carbon dioxide and olefin | 湖南工程学院 | 2024-03-26 | — | — | CN | claimed |
| CN-117567282-A | Method for preparing dimethyl adipate by palladium-catalyzed butadiene dicarbonylation | 华东理工大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116003360-B | Preparation method for synthesizing orange compounds from carbon dioxide and alkyne | 湖南工程学院 | 2024-01-23 | — | — | CN | claimed |
| CN-116237086-B | Efficient catalyst system for preparing methyl propionate by ethylene carbonylation based on antioxidant strategy | 中国科学院长春应用化学研究所 | 2023-11-03 | — | — | CN | claimed |
| CN-116851041-A | Heterogeneous catalyst for preparing methyl propionate by methyl vinyl hydro-esterification | 中国科学院过程工程研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-116854921-A | Phosphine functional polymer carrier for ethylene hydro-methyl esterification reaction and preparation method thereof | 中国科学院过程工程研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-116802187-A | Organometallic compounds | 优米科尔股份公司及两合公司 | 2023-09-22 | — | — | CN | claimed |
| CN-114849786-B | Imidazole sulfonic acid ionic liquid-based palladium phosphine complex catalyst for synthesizing methyl propionate through ethylene hydro-methyl esterification | 中国科学院过程工程研究所 | 2023-09-05 | — | — | CN | claimed |
| CN-115403465-B | Preparation method for synthesizing organic carboxylic ester by carbon dioxide and olefin | 湖南工程学院 | 2023-08-18 | — | — | CN | claimed |
| CN-102869698-A | Polymers made of renewable resources | BASF SE | 2013-01-09 | — | — | CN | claimed |
| CN-102625731-A | Palladium catalyst system comprising zwitterion and/or acid-functionalized ionic liquid | TECHNICAL UNIVERISTY OF DENMARK | 2012-08-01 | — | — | CN | claimed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | claimed |
| JP-4808401-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | claimed |
| US-7265240-B2 | With CO in the presence of a source of hydroxyl groups (water or an alcohol) and a catalyst obtained by combining a Group VIII metal or a compound thereof and a bidentate phosphine, e.g., tri(dibenzylideneacetone)di-palladium | LUCITE INTERNATIONAL UK LIMITED (GB) | 2007-09-04 | — | — | US | claimed |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-12-14 | — | — | US | claimed |
| JP-2005535695-A | — | — | 2005-11-24 | — | — | JP | claimed |
| EP-1527038-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | Lucite International UK Limited (GB) | 2005-05-04 | — | — | EP | claimed |
| WO-2004014834-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | DDT, AHR, DDC | TAAR1 403/4885SLC6A2 1181/4885TP53 3600/4885 |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | DDT, AHR, DDC | TAAR1 403/4885SLC6A2 1181/4885TP53 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.