Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948066 | 0.82 | P2RX7 (0.46) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL9828272 | 0.80 | P2RX7 (0.42) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL5508211 | 0.75 | P2RX7 (0.47) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL10274994 | 0.75 | CYP1A2 (0.48) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| Hydrochloric Acid SCHEMBL9836222 | 0.74 | P2RX7 (0.41) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| Hydrochloric Acid SCHEMBL9835431 | 0.74 | PIK3CD (0.39) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL24711921 | 0.73 | P2RX7 (0.43) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL11187153 | 0.73 | P2RX7 (0.50) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL23153416 | 0.73 | P2RX7 (0.46) | P2RX7BRD4BRD2PIK3CDDPP4 | |
| SCHEMBL10274984 | 0.73 | PIK3CD (0.44) | P2RX7BRD4BRD2PIK3CDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178345-B | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-116178345-A | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |