Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218089 | 0.84 | MAPT (0.55) | KCNJ1KCNH2MAPTALDH1A1MEN1 | |
| SCHEMBL6354500 | 0.84 | MAPT (0.47) | KCNJ1KCNH2MAPTLTA4HRAB9A | |
| SCHEMBL1127050 | 0.81 | TDP1 (0.47) | KCNJ1KCNH2MAPTLTA4HRAB9A | |
| SCHEMBL1830727 | 0.81 | NPC1 (0.55) | KCNJ1KCNH2MAPTLTA4HRAB9A | |
| SCHEMBL28057928 | 0.80 | ALDH1A1 (0.50) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4543192 | 0.80 | L3MBTL1 (0.53) | MAPTLTA4HRAB9ANPC1ALDH1A1 | |
| SCHEMBL23850950 | 0.79 | MAPT (0.63) | MAPTRAB9AALDH1A1POLBS1PR1 | |
| SCHEMBL18731512 | 0.78 | KCNJ1 (0.45) | KCNJ1KCNH2MAPTLTA4HRAB9A | |
| SCHEMBL984873 | 0.76 | KCNJ1 (0.67) | KCNJ1KCNH2MAPTLTA4HRAB9A | |
| SCHEMBL4649622 | 0.74 | NPC1 (0.57) | KCNJ1KCNH2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114481173-B | Preparation method of aniline derivative | 哈尔滨工业大学（深圳） | 2023-06-13 | — | — | CN | disclosed |