Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171401 | 0.80 | KMT2A (0.47) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL26929693 | 0.80 | NPSR1 (0.40) | KMT2AMMP2MMP9NPSR1CASP1 | |
| SCHEMBL26929567 | 0.80 | NPSR1 (0.40) | KMT2AMMP2MMP9NPSR1CASP1 | |
| SCHEMBL26929563 | 0.80 | NPSR1 (0.40) | KMT2AMMP2MMP9NPSR1CASP1 | |
| SCHEMBL2248455 | 0.79 | KMT2A (0.50) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL2021994 | 0.76 | KMT2A (0.52) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL5495801 | 0.76 | KMT2A (0.52) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL27717200 | 0.76 | KMT2A (0.52) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL6376358 | 0.75 | KMT2A (0.44) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL5260686 | 0.74 | CA2 (0.70) | KMT2AMMP2MMP9CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116429952-B | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2024-02-02 | — | — | CN | disclosed |
| CN-116429952-A | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2023-07-14 | — | — | CN | disclosed |