Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | GGH | Q92820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717200 | 1.00 | KMT2A (0.52) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL2021994 | 1.00 | KMT2A (0.52) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL4627986 | 0.87 | NAALAD2 (0.51) | MMP9NPSR1NAALAD2GGHGAA | |
| SCHEMBL4627982 | 0.87 | NAALAD2 (0.51) | MMP9NPSR1NAALAD2GGHGAA | |
| SCHEMBL13726857 | 0.87 | NAALAD2 (0.51) | MMP9NPSR1NAALAD2GGHGAA | |
| SCHEMBL2248455 | 0.85 | KMT2A (0.50) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL2021385 | 0.84 | ALDH1A1 (0.48) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL28694554 | 0.84 | ALDH1A1 (0.48) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL2021383 | 0.84 | ALDH1A1 (0.48) | KMT2AMMP9MMP2CA2CA1 | |
| SCHEMBL29908038 | 0.82 | NPSR1 (0.43) | KMT2AKIF11NPSR1NAALAD2GGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100593536-C | Method for synthesizing N-fluorene methoxycarbonyl-N-trityl-D-glutamine | GL BIOCHEM SHANGHAI LTD | 2010-03-10 | — | — | CN | claimed |
| CN-101274958-A | Bioactive peptide, preparation thereof and application thereof | OCEAN UNIV CHINA (CN) | 2008-10-01 | — | — | CN | claimed |
| CN-101219970-A | Method for synthesizing N-fluorene methoxycarbonyl-N-trityl-D-glutamine | GL BIOCHEM SHANGHAI LTD (CN) | 2008-07-16 | — | — | CN | claimed |
| CN-106414479-B | Peptides as oxytocin agonists | 豪夫迈·罗氏有限公司 | 2021-08-03 | — | — | CN | disclosed |
| EP-3784262-A1 | PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII | F. Hoffmann-La Roche AG (CH) | 2021-03-03 | — | — | EP | disclosed |
| EP-3152225-B1 | PEPTIDES AS OXYTOCIN AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-11-14 | — | — | EP | disclosed |
| EP-3151849-B1 | PEPTIDES AS OXYTOCIN AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-10-10 | — | — | EP | disclosed |
| US-9957298-B2 | Peptides as oxytocin agonists | HOFFMANN-LA ROCHE INC. (US) | 2018-05-01 | — | — | US | disclosed |
| WO-2017070157-A1 | REDOX DEHYDRATION COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2017-04-27 | — | — | WO | disclosed |
| EP-3151849-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. Hoffmann-La Roche AG (CH) | 2017-04-12 | — | — | EP | disclosed |
| EP-3152225-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. Hoffmann-La Roche AG (CH) | 2017-04-12 | — | — | EP | disclosed |
| US-6872574-B2 | Generating and screening compound libraries that are used for the identification of lead molecules, and for the parallel identification of their biological targets | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-03-29 | — | — | US | disclosed |
| US-6693168-B1 | CATALYSTS FOR PREPARING CHIRAL AMINO ACIDS | THE TRUSTEES OF BOSTON COLLEGE | 2004-02-17 | — | — | US | disclosed |
| EP-1275006-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | The Scripps Research Institute (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020182652-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-12-05 | — | — | US | disclosed |
| US-20020064799-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE OF AN ASSIGNMENT | 2002-05-30 | — | — | US | disclosed |
| US-20020045194-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-18 | — | — | US | disclosed |
| US-20020040275-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE | 2002-04-04 | — | — | US | disclosed |
| WO-2001077684-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2000015605-A2 | CHIRAL CYANOAMINES AND METHODS OF PREPARATION | TRUSTEES OF BOSTON COLLEGE (US) | 2000-03-23 | — | — | WO | disclosed |