Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502860 | 1.00 | KDM1A (0.53) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033973 | 0.87 | KDM1A (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30502867 | 0.87 | KDM1A (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033970 | 0.83 | KDM4E (0.50) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL30502863 | 0.83 | KDM4E (0.50) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL29033966 | 0.81 | KDM1A (0.51) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4307777 | 0.78 | CACNA1G (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL28825556 | 0.76 | GRIN2B (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27858170 | 0.75 | KDM1A (0.52) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL166508 | 0.74 | ALDH1A1 (0.53) | KDM4ETDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |