SCHEMBL29034616

SCHEMBL29034616

Cc1cccc(/C(=C(\C#N)c2ccccc2)c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 3/20 0.46
PARP1 P09874 1/20 0.46
ESR1 P03372 1/20 0.46
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
KCNK3 O14649 2/20 0.44
KCNK9 Q9NPC2 2/20 0.44
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MAPT P10636 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
F2 P00734 1/20 0.42
PLAU P00749 1/20 0.42
ELANE P08246 1/20 0.42
CTRB1 P17538 1/20 0.42
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034613 0.91 PARP1 (0.50) SMN1; SMN2POLBPARP1MEN1KMT2A
SCHEMBL8998951 0.84 ESR1 (0.52) SMN1; SMN2POLBESR1MEN1KMT2A
SCHEMBL8998950 0.84 ESR1 (0.52) SMN1; SMN2POLBESR1MEN1KMT2A
SCHEMBL1343904 0.83 ESR1 (0.53) POLBESR1MEN1KMT2AMAPT
SCHEMBL15494373 0.81 PARP1 (0.50) SMN1; SMN2POLBPARP1MEN1KMT2A
SCHEMBL21299091 0.81 KMO (0.47) ESR1MEN1KMT2AHDAC8KAT6A
SCHEMBL14468269 0.78 PARP1 (0.52) SMN1; SMN2POLBPARP1MEN1KMT2A
SCHEMBL31060218 0.74 CYP19A1 (0.56) ESR1MEN1KMT2AMAPTRAB9A
SCHEMBL31060887 0.74 CYP19A1 (0.56) ESR1MEN1KMT2AMAPTRAB9A
SCHEMBL31060505 0.74 CYP19A1 (0.56) ESR1MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425655-B Synthesis method of triaryl acrylonitrile 温州大学新材料与产业技术研究院 2025-03-11 CN disclosed
CN-116425655-A Synthesis method of triaryl acrylonitrile 温州大学新材料与产业技术研究院 2023-07-14 CN disclosed