Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034616 | 0.91 | SMN1; SMN2 (0.49) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL15494373 | 0.90 | PARP1 (0.50) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL14468269 | 0.82 | PARP1 (0.52) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL15688505 | 0.80 | PARP1 (0.50) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL6932732 | 0.78 | PARP1 (0.57) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL18013197 | 0.74 | PARP1 (0.47) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL1987783 | 0.73 | PARP1 (0.46) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL10177338 | 0.73 | ALDH1A1 (0.49) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL8998951 | 0.73 | ESR1 (0.52) | SMN1; SMN2MEN1KMT2AHPGDPOLB | |
| Cyanate SCHEMBL27852073 | 0.73 | PARP1 (0.55) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425655-A | Synthesis method of triaryl acrylonitrile | 温州大学新材料与产业技术研究院 | 2023-07-14 | — | — | CN | disclosed |