Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30500623 | 1.00 | HTR6 (0.47) | HTR6HRH1PTGDR2KRASPTGDR | |
| SCHEMBL29034618 | 0.84 | HTR6 (0.45) | HTR6HRH1PTGDR2PTGDRGRIN2B | |
| SCHEMBL13368695 | 0.80 | HTR6 (0.67) | HTR6HRH1GRIN2B | |
| SCHEMBL30500622 | 0.79 | HTR6 (0.49) | HTR6HRH1GRIN2B | |
| SCHEMBL29034619 | 0.78 | HTR6 (0.48) | HTR6HRH1GRIN2B | |
| SCHEMBL30500626 | 0.78 | HTR6 (0.48) | HTR6HRH1GRIN2B | |
| SCHEMBL10127795 | 0.77 | HTR6 (0.59) | HTR6HRH1GRIN2B | |
| SCHEMBL30500625 | 0.76 | HTR6 (0.46) | HTR6HRH1GRIN2B | |
| SCHEMBL30500624 | 0.73 | AKR1C3 (0.51) | HTR6HRH1PTGDR2TEAD1 | |
| SCHEMBL29034858 | 0.73 | AKR1C3 (0.51) | HTR6HRH1PTGDR2TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | disclosed |