Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30500624 | 1.00 | AKR1C3 (0.51) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 | |
| SCHEMBL11836738 | 0.75 | AKR1C3 (0.67) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 | |
| SCHEMBL11837225 | 0.74 | AKR1C3 (0.63) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 | |
| SCHEMBL11834560 | 0.74 | AKR1C3 (0.72) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 | |
| SCHEMBL11837722 | 0.74 | AKR1C3 (0.62) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 | |
| SCHEMBL13368695 | 0.74 | HTR6 (0.67) | HTR6HRH1 | |
| SCHEMBL30500623 | 0.73 | HTR6 (0.47) | HTR6HRH1PTGDR2TEAD1 | |
| SCHEMBL29034622 | 0.73 | HTR6 (0.47) | HTR6HRH1PTGDR2TEAD1 | |
| SCHEMBL30500622 | 0.73 | HTR6 (0.49) | HTR6HRH1ALDH1A1 | |
| SCHEMBL13011561 | 0.73 | PTGDR2 (0.52) | AKR1C3AKR1C2AKR1C4PTGS1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | disclosed |