Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314635 | 0.83 | NPSR1 (0.38) | ALDH1A1MAPK1LMNACA1CA2 | |
| SCHEMBL14820769 | 0.81 | KMT2A (0.35) | MAPTSMN1; SMN2 | |
| SCHEMBL12712829 | 0.78 | ACHE (0.35) | ALDH1A1SMN1; SMN2TSHRTDP1CYP2C9 | |
| SCHEMBL12013117 | 0.76 | ESR1 (0.42) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL12713096 | 0.76 | MAPT (0.36) | ALDH1A1MAPTTSHRLMNAAPEX1 | |
| SCHEMBL5002614 | 0.76 | OPRM1 (0.33) | — | |
| SCHEMBL12095490 | 0.76 | TAAR1 (0.40) | ALDH1A1MAPTMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL313072 | 0.75 | NPSR1 (0.35) | ALDH1A1NPC1TSHRTP53 | |
| SCHEMBL4320820 | 0.74 | CA1 (0.44) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL13970401 | 0.74 | CA12 (0.44) | ALDH1A1MAPK1SMN1; SMN2TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425794-A | Aryl phosphonate compound and preparation method thereof | 烟台大学 | 2023-07-14 | — | — | CN | claimed |
| CN-116425794-A | Aryl phosphonate compound and preparation method thereof | 烟台大学 | 2023-07-14 | — | — | CN | disclosed |