Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191410 | 0.84 | BACE1 (0.44) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL28873124 | 0.77 | PTPN1 (0.47) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL28862246 | 0.69 | BACE1 (0.41) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL11133453 | 0.67 | BACE1 (0.41) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL5531506 | 0.66 | BACE1 (0.64) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL668518 | 0.64 | BACE1 (0.39) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL31497105 | 0.63 | ALDH1A1 (0.47) | BACE1LMNAMAPTHTTPTPN1 | |
| SCHEMBL14663755 | 0.62 | KMT2A (0.42) | BACE1CFTRGOPCPDE4BALDH1A1 | |
| SCHEMBL9506721 | 0.62 | KMT2A (0.42) | BACE1CFTRGOPCPDE4BALDH1A1 | |
| SCHEMBL170839 | 0.62 | ALDH1A1 (0.39) | BACE1LMNAMAPTPTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194552-A | Cyclic phosphazene compounds having oxaphosphaphenanthrene-containing ring structure | 株式会社伏见制药所 | 2023-05-30 | — | — | CN | disclosed |