SCHEMBL28873124

SCHEMBL28873124

O=C1CC=C(c2ccccc2)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.47
PTPRC P08575 2/20 0.47
PTPRF P10586 1/20 0.47
CDC25B P30305 1/20 0.47
BACE1 P56817 4/20 0.42
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
HTT P42858 2/20 0.34
S100A4 P26447 1/20 0.34
HSD17B3 P37058 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8191410 0.82 BACE1 (0.44) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL8530142 0.77 AHR (0.41) PTPN1PTPRCALDH1A1MAPTHTT
SCHEMBL29035103 0.77 BACE1 (0.45) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL28905016 0.76 PTPRC (0.45) PTPRCCDC25BALDH1A1MAPK1MAOA
SCHEMBL170839 0.74 ALDH1A1 (0.39) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL29598333 0.74 ALDH1A1 (0.39) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL28447035 0.73 CDC25A (0.34) PTPN1CDC25BALDH1A1LMNAMAPT
SCHEMBL6912338 0.72 GABRA1 (0.51) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL9693191 0.72 OPRD1 (0.38) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL6919772 0.70 GABRA1 (0.54) ALDH1A1MAPK1LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093308-B Synthesis method of 1-bromo-4-phenyl naphthalene 上海固创化工新材料有限公司 2024-03-22 CN claimed
CN-115093308-A Synthesis method of 1-bromo-4-phenylnaphthalene 上海固创化工新材料有限公司 2022-09-23 CN claimed
CN-115093308-B Synthesis method of 1-bromo-4-phenyl naphthalene 上海固创化工新材料有限公司 2024-03-22 CN disclosed
CN-115093308-B Synthesis method of 1-bromo-4-phenyl naphthalene 上海固创化工新材料有限公司 2024-03-22 CN disclosed
CN-115093308-A Synthesis method of 1-bromo-4-phenylnaphthalene 上海固创化工新材料有限公司 2022-09-23 CN disclosed
CN-115093308-A Synthesis method of 1-bromo-4-phenylnaphthalene 上海固创化工新材料有限公司 2022-09-23 CN disclosed