Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617121 | 0.85 | HPGD (0.48) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL10745860 | 0.83 | PKM (0.42) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL28397771 | 0.81 | L3MBTL1 (0.63) | NPC1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL13852121 | 0.79 | L3MBTL1 (0.40) | NPC1MEN1RAB9AKMT2AHPGD | |
| SCHEMBL9099027 | 0.78 | PTPN2 (0.44) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL23931980 | 0.77 | PTPN2 (0.72) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL5578107 | 0.77 | NPC1 (0.44) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL20824909 | 0.77 | HPGD (0.37) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL1992958 | 0.77 | PTPN2 (0.43) | NPC1MEN1RAB9AKMT2APTPN2 | |
| SCHEMBL2948840 | 0.77 | MEN1 (0.50) | NPC1MEN1RAB9AKMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |