Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576877 | 0.83 | NPC1 (0.63) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL30026512 | 0.83 | NPC1 (0.63) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL22803696 | 0.76 | NPC1 (0.67) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL31668688 | 0.75 | MAOA (0.66) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL4347943 | 0.75 | NPC1 (0.69) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL5177372 | 0.73 | MAOB (0.83) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL9540720 | 0.73 | F2 (0.57) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL30621780 | 0.73 | NPC1 (0.63) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL721964 | 0.73 | MAOB (0.65) | NPC1RAB9AMAPTMAOBMAOA | |
| Hydrochloric Acid SCHEMBL12492073 | 0.73 | NPC1 (0.68) | NPC1RAB9AMAPTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845461-B | 4- (2-adamantane-1H-indol-5-yl) semicarbazide derivative and preparation method and application thereof | 浙江师范大学行知学院 | 2023-06-20 | — | — | CN | claimed |