Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035939 | 0.79 | KCNN4 (0.50) | MEN1KMT2AMAPK1CES2CES1 | |
| SCHEMBL8065635 | 0.77 | MEN1 (0.52) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL29035943 | 0.77 | TSHR (0.42) | TSHRMEN1KMT2ACES2CES1 | |
| SCHEMBL29035981 | 0.72 | MAPT (0.47) | MEN1KMT2AMAPK1CES2CES1 | |
| SCHEMBL8255103 | 0.68 | MIF (0.45) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL4312243 | 0.68 | MIF (0.50) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL12869567 | 0.67 | LMNA (0.47) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL4591880 | 0.67 | MIF (0.54) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL23077098 | 0.67 | MIF (0.44) | MIFTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL3557871 | 0.67 | KMT2A (0.52) | MIFTSHRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115231995-A | Mono-fluoro dibromo acetone derivative and preparation and application thereof | 上海应用技术大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115231995-A | Mono-fluoro dibromo acetone derivative and preparation and application thereof | 上海应用技术大学 | 2022-10-25 | — | — | CN | disclosed |