Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465707 | 1.00 | PLA2G2C (0.44) | PLA2G2CMCHR1GPR84ALDH1A1FFAR4 | |
| SCHEMBL10792302 | 0.99 | PLA2G2C (0.42) | PLA2G2CMCHR1GPR84ALDH1A1FFAR4 | |
| SCHEMBL30721168 | 0.95 | PLA2G2C (0.46) | PLA2G2CMCHR1GPR84ALDH1A1FFAR4 | |
| SCHEMBL5474740 | 0.89 | CA12 (0.44) | PLA2G2CALDH1A1CA2CA9CA1 | |
| SCHEMBL4303888 | 0.89 | CA12 (0.44) | PLA2G2CALDH1A1CA2CA9CA1 | |
| SCHEMBL5477848 | 0.89 | CA12 (0.44) | PLA2G2CALDH1A1CA2CA9CA1 | |
| SCHEMBL5071377 | 0.88 | PLA2G2C (0.45) | PLA2G2CMCHR1GPR84ALDH1A1CA2 | |
| SCHEMBL13219933 | 0.88 | PLA2G2C (0.45) | PLA2G2CMCHR1GPR84ALDH1A1CA2 | |
| SCHEMBL9625787 | 0.88 | PLA2G2C (0.45) | PLA2G2CMCHR1GPR84ALDH1A1CA2 | |
| SCHEMBL9625505 | 0.88 | PLA2G2C (0.45) | PLA2G2CMCHR1GPR84ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833993-B2 | Immunomodulatory compounds and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1439184-B1 | Immunological adjuvant compounds | EISAI R&D MAN CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-7560584-B2 | Immunomodulatory compounds and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20050164988-A1 | Immunomodulatory compounds and methods of use thereof | EISAI CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| US-20050123566-A1 | Immunomodulatory compounds and methods of use thereof | EISAI CO., LTD (JP) | 2005-06-09 | — | — | US | disclosed |
| US-6835721-B2 | Phosphate or ammonium compounds that function as immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases | EISAI CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| EP-1439184-A1 | Immunological adjuvant compounds | Eisai Co., Ltd. (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1147117-B1 | IMMUNOLOGICAL ADJUVANT COMPOUNDS | EISAI CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20040006242-A1 | Immunomodulatory compounds and method of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-01-08 | — | — | US | disclosed |
| US-20030153532-A1 | Immunomodulatory compounds and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-08-14 | — | — | US | disclosed |
| US-6551600-B2 | A phosphate derivative when co-administered with antigens such as vaccines for bacterial and viral diseases function as immunological adjuvant | EISAI CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20020176861-A1 | Immunological adjuvant compounds compositions and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2002-11-28 | — | — | US | disclosed |
| US-6290973-B1 | VACCINES FOR BACTERIAL AND VIRAL DISEASES | EISAI CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050123566-A1 | Immunomodulatory compounds and methods of use thereof | TLR5, TLR3, TLR6 | PLA2G2C 230/4885MCHR1 2418/4885GPR84 756/4885 |
| US-20020176861-A1 | Immunological adjuvant compounds compositions and methods of use thereof | TLR5, MYD88, TLR3 | PLA2G2C 61/4885MCHR1 2944/4885GPR84 511/4885 |
| US-20050164988-A1 | Immunomodulatory compounds and methods of use thereof | TSLP, IL5, ICOS | PLA2G2C 600/4885MCHR1 2495/4885GPR84 704/4885 |
| US-20040006242-A1 | Immunomodulatory compounds and method of use thereof | IL5, ICOS, TSLP | PLA2G2C 679/4885MCHR1 2434/4885GPR84 789/4885 |
| US-20030153532-A1 | Immunomodulatory compounds and methods of use thereof | TLR5, TLR3, TLR6 | PLA2G2C 230/4885MCHR1 2418/4885GPR84 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.