SCHEMBL29036741

SCHEMBL29036741

CCCCCCCCCCCc1cn[c]c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.42
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
HSPD1 P10809 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749230 0.74 TDP1 (0.46) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL21052798 0.74 TDP1 (0.46) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL5745373 0.74 TDP1 (0.46) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL5748773 0.74 TDP1 (0.46) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL19697178 0.71 TDP1 (0.49) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL20467132 0.71 TDP1 (0.49) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL21230532 0.71 TDP1 (0.49) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL27563659 0.71 TDP1 (0.57) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL5836620 0.71 TDP1 (0.47) PTGS2CYP3A4TDP1L3MBTL1ESR1
SCHEMBL922743 0.70 PTGS2 (0.43) PTGS2CYP3A4ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116249528-A Cold treating agent and antiviral agent 株式会社大塚制药工场 2023-06-09 CN disclosed