SCHEMBL29037249

SCHEMBL29037249

CCOC(=O)c1ccc(F)c(F)c1C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA7 P43166 3/20 0.49
CA9 Q16790 3/20 0.49
CA14 Q9ULX7 3/20 0.49
NPSR1 Q6W5P4 2/20 0.48
HTT P42858 2/20 0.48
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 1/20 0.45
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
HPGD P15428 2/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1958113 0.87 TSHR (0.57) TSHRCA12CA1CA2CA7
SCHEMBL1997194 0.87 CA12 (0.53) TSHRCA12CA1CA2CA7
SCHEMBL22261452 0.84 TSHR (0.53) TSHRCA12CA1CA2CA7
SCHEMBL29604715 0.84 TSHR (0.53) TSHRCA12CA1CA2CA7
SCHEMBL28161602 0.83 TSHR (0.65) TSHRCA12CA1CA2CA7
SCHEMBL22261518 0.81 TSHR (0.50) TSHRCA12CA1CA2CA7
SCHEMBL20607744 0.81 TSHR (0.50) TSHRCA12CA1CA2CA7
SCHEMBL8107311 0.81 ALDH1A1 (0.47) TSHRCA12CA1CA2CA7
SCHEMBL7496480 0.81 TSHR (0.53) TSHRCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL687729 0.80 ALDH1A1 (0.46) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107880902-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司 2023-07-25 CN disclosed