SCHEMBL1997194

SCHEMBL1997194

CCOC(=O)c1c(F)ccc(F)c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
TSHR P16473 2/20 0.47
NPSR1 Q6W5P4 5/20 0.44
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 2/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
GAA P10253 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31237061 0.89 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL29037249 0.87 TSHR (0.52) CA12CA1CA2CA7CA9
SCHEMBL5431033 0.86 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL8107311 0.86 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL28706649 0.86 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL23817272 0.86 CA12 (0.40) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL687729 0.84 ALDH1A1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL24863513 0.84 PRKCZ (0.50) CA12CA1CA2CA7CA9
SCHEMBL12945976 0.83 TP53 (0.45) CA12CA1CA2CA7CA9
SCHEMBL31237051 0.83 CA12 (0.45) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed