Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22016208 | 0.78 | CHRNB2 (0.35) | BRD4TDP1 | |
| SCHEMBL15934909 | 0.77 | ALDH1A1 (0.37) | BRD4TDP1 | |
| SCHEMBL171024 | 0.75 | BRD4 (0.40) | BRD4AURKATTKAURKBINCENP | |
| SCHEMBL19869652 | 0.74 | BRD4 (0.42) | BRD4TDP1AURKATTKAURKB | |
| SCHEMBL13523501 | 0.73 | SYK (0.38) | BRD4 | |
| SCHEMBL23164339 | 0.72 | BRD4 (0.38) | BRD4AURKATTKAURKBINCENP | |
| SCHEMBL11987749 | 0.72 | BRD4 (0.38) | BRD4AURKATTKAURKBINCENP | |
| SCHEMBL13512616 | 0.72 | AURKA (0.40) | BRD4AURKATTKAURKBINCENP | |
| Bromide SCHEMBL1203957 | 0.71 | BRD4 (0.38) | BRD4AURKATTKAURKBINCENP | |
| Bromide SCHEMBL1203956 | 0.69 | BRD4 (0.37) | BRD4AURKATTKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462635-A | Pyrazine-1 (2H) -2-oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-07-21 | — | — | CN | disclosed |