Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24373092 | 0.78 | KDM5B (0.32) | USP2LMNAHPGDHSD17B10 | |
| SCHEMBL16631954 | 0.72 | — | — | |
| SCHEMBL1558808 | 0.72 | — | — | |
| SCHEMBL17399895 | 0.70 | — | — | |
| SCHEMBL7434051 | 0.65 | PDGFRB (0.52) | HPGD | |
| SCHEMBL9682981 | 0.63 | NPSR1 (0.45) | HPGDERCC1ERCC4 | |
| SCHEMBL31305776 | 0.63 | FFAR1 (0.31) | — | |
| SCHEMBL2633430 | 0.63 | ALDH1A1 (0.39) | USP2LMNAHPGDHSD17B10 | |
| SCHEMBL1645331 | 0.61 | — | — | |
| SCHEMBL2635489 | 0.61 | ERCC1 (0.50) | ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-116462635-A | Pyrazine-1 (2H) -2-oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-07-21 | — | — | CN | disclosed |