Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537996 | 1.00 | DDB1 (0.41) | DDB1CRBNPKMTSHRPOLB | |
| SCHEMBL16932281 | 0.87 | DDB1 (0.43) | DDB1CRBNPKMTSHRPOLB | |
| SCHEMBL30538044 | 0.84 | CTSC (0.30) | — | |
| SCHEMBL29038870 | 0.84 | MIF (0.36) | POLBALDH1A1MEN1KMT2ANOS3 | |
| SCHEMBL30538024 | 0.84 | MIF (0.36) | POLBALDH1A1MEN1KMT2ANOS3 | |
| SCHEMBL29038850 | 0.84 | CTSC (0.30) | — | |
| SCHEMBL782545 | 0.82 | DDB1 (0.42) | DDB1CRBNPKMTSHRGPR55 | |
| SCHEMBL30538026 | 0.82 | SIGMAR1 (0.41) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL29038843 | 0.82 | ALDH1A1 (0.42) | TSHRPOLBLMNAALDH1A1MEN1 | |
| SCHEMBL30538030 | 0.82 | ALDH1A1 (0.42) | TSHRPOLBLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483492-B | Dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2023-07-21 | — | — | CN | disclosed |