Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.47 |
| ▸ | USP19 | O94966 | 1/20 | 0.47 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364161 | 0.81 | NR4A2 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C19MEN1 | |
| SCHEMBL2364162 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL7738122 | 0.78 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL762311 | 0.77 | NR4A2 (0.62) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL7796083 | 0.76 | NOTUM (0.50) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL11454303 | 0.75 | SMN1; SMN2 (0.47) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL15428324 | 0.75 | USP1 (0.47) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL8924884 | 0.75 | USP1 (0.47) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL869242 | 0.75 | GAA (0.51) | USP1USP19WDR48NPC1RAB9A | |
| SCHEMBL5540292 | 0.75 | USP1 (0.47) | USP1USP19WDR48NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806142-B1 | Method for the production of (poly)peptides by using truncated variants of the SV 40 large T antigen with an intact N terminus | RHEIN BIOTECH PROZ & PROD GMBH (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-1806142-A1 | Method for the production of (poly)peptides by using truncated variants of the SV 40 large T antigen with an intact N terminus | VaDeCo Biotech GmbH & Co. KG (DE) | 2007-07-11 | — | — | EP | disclosed |
| EP-1117803-B1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | VADECO BIOTECH GMBH & CO KG (DE) | 2006-12-13 | — | — | EP | disclosed |
| EP-1117803-A1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | REIMANN, Hansjurg (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020606-A1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | REIMANN HANSJOERG (DE) | 2000-04-13 | — | — | WO | disclosed |